biolitec, the worldwide leader in Photodynamic Therapy (PDT), manufactures every necessary product for PDT:

• Advanced diode laser systems that are ideal for a broad range of photosensitizers.
  
  
• Innovative and efficient accessories, including fiber optic delivery systems and laser probes.
  
  
• Highly specialized photosensitizers, integral for several practical PDT applications.

Photosensitizers

biolitec’s phototherapeutic agents are extracted from bacteria through various chemical and pharmaceutical processes. Red light triggers a reaction in these substances, while avoiding thermal damage. Laser wavelength is matched to the absorptive properties of the phototherapeutic agent. biolitec’s PDT lasers use wavelengths ranging from 630nm to 760nm.

The phototherapeutic agents were developed through more than ten years of research in specialized laboratories. There are several types of photosensitizers: One group is obtained from blood and suited for just a few special applications due to the low activation wavelength (630nm) of the active ingredient.

Another group of photosensitizers are activated at higher wavelengths, which facilitates treatment of deeper tissue areas. Photosensitizers currently in the development stage include vector and multiplicator molecules for an even greater selectivity of the phototherapeutic agents.

With biolitec’s patented parachute technology, photosensitizers accumulate at critical locations in the cell membrane, which will substantially increase their lethal effect and boost their efficacy by a factor of somewhere between 20 and 100.

Probes and Optical Fibers

Quartz-based optical fibers permit the efficient and flexible transmission of laser radiation to locations in the body that are difficult to access. The customized fiber ends (i.e. where the radiation is emitted) are typically introduced into the body by endoscopes or catheters.

Lasers

In addition to the development of highly specialized photosensitizers, the practical application of PDT hinges on the availability of small, low-maintenance diode lasers that generate the necessary radiation to activate photosensitizers.

PDT Clinical Trials

Permanent Hair Removal – The company’s patent-pending, photodynamic-based method of permanent hair removal was successfully tested utilizing inexpensive light sources.

Oncology, Tumors, and Dysplasia - biolitec is currently studying the use of PDT for treating several types of cancer, tumors, and dysplasia, including:

• Breast Cancer
• Prostate Cancer
• Barrett's Esophagus
• Dysplasia: Neck of the Cervix